About Benchtop SPR with analysis module
The new BI-2500 benchtop SPR system offers 3-channel flow mode and delivers high quality binding response for low immobilization and small molecule (<100 Da) detection. Its innovative modular design provides users with optimal flexibility to choose amongst various analysis modules for life science, electrochemistry, and biosensing in liquid and gas phase SPR applications. In addition, its fast detection is ideal for the study of fast kinetics of redox-induced conformational changes in proteins and other biomolecules.Advanced Biomolecular Interaction AnalysisThis benchtop SPR analyzer empowers researchers to investigate molecular interactions and binding kinetics efficiently. Its gold-coated sensor chips, supported by real-time LED/laser optical excitation, deliver precise detection, while the robust integrated software simplifies the interpretation of complex interaction data.
Superior Sensitivity and AccuracyEngineered for excellence, the system's baseline noise is less than 0.05 RU, with a resolution down to 0.1 RU and accuracy of 2%. Consistent temperature control ensures reliable and reproducible results, key for scientific studies requiring high sensitivity, such as drug discovery and protein characterization.
Efficient Operation and User-Friendly InterfaceWith automated sample injection and maintenance, users can perform up to 100 runs per day. The touchscreen LCD and computer interface simplify operation, while the multilingual UI and multiple data formats (CSV, PDF, proprietary) enable effortless integration into diverse laboratory settings.
FAQ's of Benchtop SPR with analysis module:
Q: How does the benchtop SPR analyzer facilitate biomolecular interaction analysis?
A: The analyzer utilizes gold-coated glass sensor chips and highly sensitive optical excitation (LED/laser-based) to detect molecular interactions in real time. Integrated software supports affinity, kinetics, and concentration analysis, providing comprehensive insights into biomolecular binding events.
Q: What is the recommended sample volume for each injection when using this SPR system?
A: For optimal performance, the SPR analyzer requires a sample volume between 20 and 80 microliters per injection. This ensures effective interaction detection within the flow cell while conserving valuable reagents.
Q: When should users perform cleaning or maintenance on the SPR analyzer?
A: Routine maintenance is supported through automated washing and purging protocols, which the system initiates based on usage and operational schedules. This automated approach helps sustain performance and minimizes downtime.
Q: Where is the SPR analyzer typically used, and what are its primary applications?
A: This instrument is ideal for laboratory analytical environments, especially in life science research and pharmaceutical labs. Key applications include biomolecular interaction studies, binding kinetics analysis, and concentration measurements of interacting species.
Q: What is the process for analyzing a sample using the integrated analysis module?
A: Users load samples either manually or via the auto-sampler, initiate runs through the computer-controlled analysis module, and view results on the 7" touchscreen or computer interface. The software enables detailed kinetic, affinity, and concentration analyses, with data available in multiple formats.
Q: What are the benefits of its automated sample injection and maintenance features?
A: Automation enhances efficiency and reproducibility, allowing for up to 100 runs per day and consistent cleaning. This reduces manual intervention, ensures data integrity, and improves throughput in demanding laboratory workflows.
Q: How does temperature stability impact the results in SPR analysis?
A: With stability maintained at 0.1C, the analyzer provides highly reproducible conditions for sensitive molecular experiments. Accurate temperature control is critical for reliable kinetic measurements and consistent experimental outcomes.